ncRNA name | hsa-miR-124 |
ncRNA Category | miRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | transfection, qRT-PCR, Western blot, Phalloidin staining, immunocytochemistry, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | This study describes the regulation of EMT in RPE cells by TGF-β1/miR-124/RHOG signaling and suggests that the supplement of miR-124 exogenously would be a valuable therapeutic approach for the prevention or treatment of proliferative vitreoretinopathy. |
PubMed ID | 26746014 |
Year | 2016 |
Title | MicroRNA-124 Controls Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in the Retinal Pigment Epithelium by Targeting RHOG. |
Drug-related ncRNA | NO |
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